Validation

Synthetic clinical data should be measurable.

Synset reports validation by tier, separating certified trajectory support, accepted-only audit results, withheld-prior validation, self-consistency testing, and held-out future validation when available.

Validation Tiers

Tier 1: Held-Out Future Validation

Uses real observed future data intentionally hidden during generation.

  • Acute: pending local row-level future trajectory table.
  • Chronic: pending sufficient row-level repeated-visit future data.

Tier 2: Independent / Withheld Validation

Uses independent validators or withheld empirical-prior constraints not used as the final public claim of patient-future accuracy.

  • Acute: 0 / 14,143 accepted-only validator violations.
  • Chronic: 0 / 3,953 final withheld-prior violations after release gating.

Tier 3: Certified Self-Consistency

Masks later certified synthetic segments and verifies regenerated continuations remain within the certified support envelope.

  • Measured for acute and chronic.
  • Internal stability measure.
  • Not ground-truth accuracy.

Acute results

Support-certified horizon: 96 sequential hourly transitions.

Support-certified horizon
96 sequential hourly transitions.
Accepted-only validator audit
0 / 14,143 accepted acute candidates.
Conservative upper bound
~0.021%.
Yield improvement
~7x final-horizon certified yield with reanchoring.

Required caveat: These are not held-out future patient accuracy claims.

Chronic results

Current stage: aggregate-prior-distilled prototype.

Current stage
aggregate-prior-distilled prototype.
Withheld-prior validation after optimization
0 / 3,953 final audit checks.
Conservative upper bound
~0.076%.

Required caveat: This is withheld empirical-prior validation, not held-out patient-future accuracy.

Build validation into the generation workflow.

Candidate trajectories are generated, checked, filtered, and audited before they are treated as releasable synthetic data.